Vitamin C (as Ascorbic Acid, Rose Hips, Acerola Cherry)
1,000 mg
1,111%
Bioflavonoid Concentrate (from Citrus)
50 mg
*
Top Medical Research Studies
9
Vitamin C enhances blood clotting
Ascorbic acid improves thrombotic function of platelets during living donor liver transplantation by modulating the function of the E3 ubiquitin ligases c-Cbl and Cbl-b.
We sought to understand how ascorbic acid, commonly known as vitamin C, impacts blood clotting during living donor liver transplantation (LDLT). In our study, we analyzed blood samples from 21 recipients before and after their surgeries.
We employed a well-structured approach, using rotational thromboelastography (TEG) and western blot analysis to scrutinize fibrinolysis and the functionality of specific proteins involved in clotting. Blood samples were tested in three distinct groups, one receiving vitamin C, to see its effects on clot rigidity and fibrinolysis.
Our findings revealed that ascorbic acid notably reduced fibrinolysis, which refers to the breakdown of blood clots, and improved the rigidity of the clots formed. Additionally, we observed that levels of a protein called Cbl-b were higher in those receiving vitamin C, while another protein, c-Cbl, showed reduced phosphorylation. These functional changes might explain how vitamin C supports better clotting during surgeries.
This study indicates that vitamin C could be a beneficial treatment to consider during LDLT to manage hyperfibrinolysis, thus promoting better outcomes for patients undergoing these complex procedures.
Read More
8
Scurvy-related DVT treated with vitamin C
Pediatric scurvy case report: a novel presentation with deep vein thrombosis secondary to large bilateral spontaneous iliac subperiosteal hematomas.
We explored a unique case of a 14-year-old boy with autism who presented with deep vein thrombosis (DVT) due to large bilateral subperiosteal hematomas caused by vitamin C deficiency, known as scurvy. This rare situation is noteworthy as scurvy is typically associated with other symptoms, but here it led to an unusual complication of DVT.
During our investigation, we observed that after administering vitamin C replacement, the patient's condition improved significantly. Follow-up imaging showed that both the DVT and the hematomas resolved. This outcome suggests that vitamin C can potentially have a positive impact in cases where blood clots are related to underlying deficiencies.
However, we must clarify that while vitamin C treatment appeared beneficial in this specific situation, our findings are based on a single case. Thus, further research would be essential to understand its broader implications on DVT treatment and the role of vitamin C in blood clot scenarios.
Read More
8
Vitamin C reduces clotting factors
Vitamin C suppresses lipopolysaccharide-induced procoagulant response of human monocyte-derived macrophages.
We explored how vitamin C influences blood clotting in response to inflammation, specifically focusing on how it affects certain proteins involved in this process. In our study, we tested vitamin C at clinically relevant doses within human monocyte-derived macrophages. This investigation involved examining its effects on tissue factor (TF) and Factor VII Activating Protease (FSAP), two key proteins that play a role in triggering blood clotting after exposure to lipopolysaccharide (LPS), which is often associated with infection and inflammation.
Our findings showed that vitamin C can prevent the activation of a protein called NF-kB, which is crucial for the inflammatory response. It turns out that vitamin C not only reduces the DNA-binding activity of NF-kB but also decreases the expression of TF and FSAP, suggesting it can effectively modulate clots formed in response to inflammation. Overall, we observed that vitamin C offers promising benefits in altering pro-inflammatory and pro-coagulation processes.
This means that aside from being a potent antioxidant, vitamin C might also support cardiovascular health by reducing the risk factors associated with clot formation during inflammatory responses. While more research is needed to validate these effects fully, our study opens the door to the potential role of vitamin C in managing clot-related disorders linked to inflammation.
Read More
Most Useful Reviews
9
Skin tone improvement
Suddenly, I really liked it - it’s no secret that vitamin C is often taken as an adaptogen before the cold season to help strengthen the immune system. This particular supplement contains rutin and hesperidin - vital bioflavonoids for those concerned about their blood vessels. I have second-stage varicose veins and spider veins on my face. With this supplement, I noticed my skin became lighter, the tone was even, and bruises disappeared quickly. I recommend it for strengthening and healthy blood vessels. The capsules are medium-sized, easy to swallow, and the contents can be poured into juice. They have a pleasant herbal scent and do not cause gastrointestinal issues, if that's a concern for anyone.
Read More
9
Bruising resolved
I struggled with easily bruising, and my blood work indicated large platelets. After starting this supplement, I am pleased to report that I no longer experience bruising issues.
Read More
9
Supports veins well
Excellent! This is my favourite form of vitamin C! It’s beneficial for veins and blood vessels! The dosage is 500 mg at a time for adults! If this was useful, please give it a thumbs up!
In our investigation, we looked at how vitamin C, in combination with a fibrin clot, influences the healing of Achilles tendon injuries in rats. We used 52 adult Wistar-Albino rats and divided them into four distinct groups to assess various treatments.
The results showed that vitamin C, when paired with fibrin clot, significantly improved tendon healing. Not only did it enhance the mechanical strength of the tendon, but it also led to better histological and biochemical outcomes, suggesting a more robust healing process. We noted increased levels of important growth factors in the groups treated with fibrin clot and vitamin C.
Importantly, the findings indicated that vitamin C plays a beneficial role in recovery, especially when combined with other treatment strategies. While further research may be necessary to fully understand its isolated effects, the data suggests that vitamin C is a valuable component in the healing bundle for Achilles tendon injuries.
Read More
9
Vitamin C enhances blood clotting
Ascorbic acid improves thrombotic function of platelets during living donor liver transplantation by modulating the function of the E3 ubiquitin ligases c-Cbl and Cbl-b.
We sought to understand how ascorbic acid, commonly known as vitamin C, impacts blood clotting during living donor liver transplantation (LDLT). In our study, we analyzed blood samples from 21 recipients before and after their surgeries.
We employed a well-structured approach, using rotational thromboelastography (TEG) and western blot analysis to scrutinize fibrinolysis and the functionality of specific proteins involved in clotting. Blood samples were tested in three distinct groups, one receiving vitamin C, to see its effects on clot rigidity and fibrinolysis.
Our findings revealed that ascorbic acid notably reduced fibrinolysis, which refers to the breakdown of blood clots, and improved the rigidity of the clots formed. Additionally, we observed that levels of a protein called Cbl-b were higher in those receiving vitamin C, while another protein, c-Cbl, showed reduced phosphorylation. These functional changes might explain how vitamin C supports better clotting during surgeries.
This study indicates that vitamin C could be a beneficial treatment to consider during LDLT to manage hyperfibrinolysis, thus promoting better outcomes for patients undergoing these complex procedures.
Read More
8
Scurvy-related DVT treated with vitamin C
Pediatric scurvy case report: a novel presentation with deep vein thrombosis secondary to large bilateral spontaneous iliac subperiosteal hematomas.
We explored a unique case of a 14-year-old boy with autism who presented with deep vein thrombosis (DVT) due to large bilateral subperiosteal hematomas caused by vitamin C deficiency, known as scurvy. This rare situation is noteworthy as scurvy is typically associated with other symptoms, but here it led to an unusual complication of DVT.
During our investigation, we observed that after administering vitamin C replacement, the patient's condition improved significantly. Follow-up imaging showed that both the DVT and the hematomas resolved. This outcome suggests that vitamin C can potentially have a positive impact in cases where blood clots are related to underlying deficiencies.
However, we must clarify that while vitamin C treatment appeared beneficial in this specific situation, our findings are based on a single case. Thus, further research would be essential to understand its broader implications on DVT treatment and the role of vitamin C in blood clot scenarios.
Read More
8
Vitamin C reduces clotting factors
Vitamin C suppresses lipopolysaccharide-induced procoagulant response of human monocyte-derived macrophages.
We explored how vitamin C influences blood clotting in response to inflammation, specifically focusing on how it affects certain proteins involved in this process. In our study, we tested vitamin C at clinically relevant doses within human monocyte-derived macrophages. This investigation involved examining its effects on tissue factor (TF) and Factor VII Activating Protease (FSAP), two key proteins that play a role in triggering blood clotting after exposure to lipopolysaccharide (LPS), which is often associated with infection and inflammation.
Our findings showed that vitamin C can prevent the activation of a protein called NF-kB, which is crucial for the inflammatory response. It turns out that vitamin C not only reduces the DNA-binding activity of NF-kB but also decreases the expression of TF and FSAP, suggesting it can effectively modulate clots formed in response to inflammation. Overall, we observed that vitamin C offers promising benefits in altering pro-inflammatory and pro-coagulation processes.
This means that aside from being a potent antioxidant, vitamin C might also support cardiovascular health by reducing the risk factors associated with clot formation during inflammatory responses. While more research is needed to validate these effects fully, our study opens the door to the potential role of vitamin C in managing clot-related disorders linked to inflammation.
Read More
4
Vitamin C lowers blood clot risks
Ascorbic acid as an adjunctive therapy in critically ill patients with COVID-19: a propensity score matched study.
We explored the use of ascorbic acid, commonly known as vitamin C, as an additional treatment option for patients critically ill with COVID-19. This study was conducted across two large hospitals in Saudi Arabia and involved a thorough look at the outcomes for these patients, especially concerning blood clotting and overall health.
After evaluating 739 patients, 296 were matched for a fair comparison. Notably, the findings suggest that while there was no significant reduction in mortality rates for those receiving vitamin C compared to those who did not, the use of vitamin C was linked to a lower occurrence of thrombosis—an abnormal blood clotting condition. The incidence of thrombosis in the vitamin C group was 6.1%, compared to 13% in the non-vitamin C group, indicating a possible protective effect against blood clots.
Ultimately, while the addition of vitamin C did not show a direct mortality benefit, it may offer some hope for reducing blood clot complications in these severely affected patients. However, further research will be necessary to validate these findings and clarify the role of vitamin C in treatment protocols for COVID-19.
Suddenly, I really liked it - it’s no secret that vitamin C is often taken as an adaptogen before the cold season to help strengthen the immune system. This particular supplement contains rutin and hesperidin - vital bioflavonoids for those concerned about their blood vessels. I have second-stage varicose veins and spider veins on my face. With this supplement, I noticed my skin became lighter, the tone was even, and bruises disappeared quickly. I recommend it for strengthening and healthy blood vessels. The capsules are medium-sized, easy to swallow, and the contents can be poured into juice. They have a pleasant herbal scent and do not cause gastrointestinal issues, if that's a concern for anyone.
Read More
9
Bruising resolved
I struggled with easily bruising, and my blood work indicated large platelets. After starting this supplement, I am pleased to report that I no longer experience bruising issues.
Read More
9
Supports veins well
Excellent! This is my favourite form of vitamin C! It’s beneficial for veins and blood vessels! The dosage is 500 mg at a time for adults! If this was useful, please give it a thumbs up!
Read More
7.5
Strengthens blood vessels
Vitamin C with bioflavonoids is of excellent quality, with digestible and natural ingredients. The composition is superb, and vitamin C is well absorbed alongside bioflavonoids. The jar and capsules are of average size and well-packaged. My stomach tolerates it well. This unique formula offers comprehensive protection for the immune system of both children and adults, stimulates collagen synthesis, and strengthens the walls of blood vessels, including those prone to varicose veins.
Read More
7.5
Effective vessel support
A very useful formula. Bioflavonoids effectively complement vitamin C, enhancing their ability to strengthen blood vessels and capillaries. The dosage is excellent, providing enough for several courses for the whole family.
A blood clot is a mass of blood that changes from a liquid to a gel, effectively forming a plug that can stop bleeding. This natural process, known as coagulation, is critical for preventing excessive blood loss when you sustain an injury. Blood clots can occur in various areas of the body, typically at the site of a wound, but they can also form within blood vessels without an obvious injury, which may lead to serious health complications.
While blood clots are essential for healing, they can pose significant health risks if they form inappropriately. For example, a deep vein thrombosis (DVT) occurs when a clot forms in a deep vein, usually in the legs, and can travel to the lungs, causing a life-threatening condition called a pulmonary embolism. Risk factors for blood clots include prolonged immobility, certain medical conditions, and the use of specific medications, among others. It’s important to recognize the symptoms of abnormal clotting, such as swelling, pain, and redness in the affected area, and seek medical attention if they occur.
Vitamin C, also known as ascorbic acid, is a water-soluble vitamin that plays a critical role in numerous bodily functions. As an essential nutrient, it contributes to the growth and repair of tissues in the body, and it is vital for the production of collagen, an important protein that helps maintain skin, cartilage, tendons, ligaments, and blood vessels. Additionally, Vitamin C acts as a powerful antioxidant, which means it helps combat free radicals—unstable molecules that can cause oxidative stress and contribute to various chronic diseases.
Moreover, Vitamin C enhances iron absorption from plant-based foods, making it a vital component for those following vegetarian or vegan diets. While many people get sufficient Vitamin C from a well-balanced diet that includes fruits and vegetables like oranges, strawberries, kiwi, broccoli, and bell peppers, some individuals might require supplementation. It's generally recommended to stay within the daily intake guidelines, as excessive consumption can lead to gastrointestinal disturbances. Overall, Vitamin C is not just a skincare celebrity—it's a fundamental part of maintaining overall health and well-being.
Vitamin C is renowned for its immune-boosting properties and its role as a powerful antioxidant, but its effects on blood clotting are somewhat nuanced. While vitamin C is essential for overall health and the maintenance of healthy blood vessels, there's limited direct evidence to suggest that it aids in the prevention or treatment of blood clots. Some studies indicate that vitamin C may contribute to healthier circulation and could potentially reduce the risk of conditions associated with blood clotting, such as cardiovascular diseases.
However, relying solely on vitamin C for managing or preventing blood clots is not recommended. It is always best to consult a healthcare professional before making any changes to your diet or supplementation routine, especially if you are at risk for blood clots or have existing health concerns. While vitamin C can play a role in overall vascular health, it should be part of a holistic approach that includes a balanced diet, regular exercise, and, if necessary, medical treatment.
Based on user reviews, the timeline for experiencing results from this supplement for blood clot and vascular health can vary. Several users have reported noticing improvements relatively quickly. For instance, one reviewer mentioned that they no longer experienced bruising issues shortly after starting the supplement, indicating a potentially rapid response to the formulation Read Review. Others noted improvements in skin tone and the speed at which bruises disappeared, suggesting that positive changes might be observed within a few weeks of consistent use Read Review.
Overall, while individual experiences may vary, initial results can often be seen within a short period, with continuous improvement possible over time as the supplement aids in strengthening blood vessels. Many users have expressed satisfaction with the efficacy of the product, highlighting its formulation's beneficial properties for vein and vessel health Read Review. For best outcomes, consistent consumption and adherence to the recommended dosage seem to be crucial.
The research surrounding vitamin C's impact on blood clotting presents a mixed picture. Several studies indicate that vitamin C may have a beneficial role in reducing blood clot complications, particularly in specific clinical contexts. For example, in critically ill COVID-19 patients, vitamin C was linked to a decreased incidence of thrombosis, with rates of 6.1% in those receiving the supplement compared to 13% in the control group [2]. Additionally, another study showed that vitamin C helped improve clot rigidity during liver transplantation, potentially aiding in managing hyperfibrinolysis [4]. This suggests that vitamin C could support better clotting outcomes in certain medical scenarios.
However, caution is warranted, as other research has indicated that high doses of vitamin C may increase the risk of blood clot formation, especially in cancer patients, where it heightened the procoagulant tendencies of red blood cells [6]. Furthermore, while vitamin C showed promise in cases involving inflammatory conditions where clotting is a concern, the potential risks associated with its high-dose administration, particularly in vulnerable populations, suggest that further investigation is necessary [5]. Overall, while there are emerging benefits tied to vitamin C and blood clot management, the variability in findings calls for a careful, case-by-case approach when considering vitamin C supplementation for blood clot issues.
Based on user reviews, many individuals have reported positive improvements in their symptoms related to vascular health after using this supplement. Specifically, one user with second-stage varicose veins noted that their skin tone became lighter and more even, and they observed a quicker disappearance of bruises, thus recommending it for strengthening blood vessels overall Read Review. Another reviewer mentioned a significant reduction in bruising, stating that after starting the supplement, they no longer experienced issues with easily bruising, indicating a potential efficacy in improving blood vessel resilience Read Review.
Moreover, users have praised the supplement for its comprehensive formulation that combines vitamin C with bioflavonoids like rutin and hesperidin, which appear to enhance the supplement’s ability to support vascular health. One review highlighted how the unique formula not only stimulates collagen synthesis but also strengthens blood vessel walls, especially beneficial for those prone to varicose veins Read Review. Overall, while individual results can vary greatly, these anecdotal experiences collectively suggest that consistent use of this supplement may lead to noticeable improvements in vascular-related symptoms and skin appearance.
Based on user reviews, many individuals have reported positive experiences when combining this supplement with other supplements for blood clot management. Specifically, users have highlighted the benefit of taking vitamin C alongside bioflavonoids like rutin and hesperidin to enhance vascular health. One reviewer noted that the combination of these ingredients effectively supports blood vessel strength, making it particularly beneficial for those concerned about varicose veins and bruising issues Read Review. Another user shared that since starting the supplement, they no longer experienced problems with easy bruising, suggesting that the formulation may be quite effective in improving overall blood vessel resilience Read Review.
Furthermore, several users emphasized the importance of the specific combination in their regimens. One individual described the supplement as containing vital bioflavonoids that not only enhance vitamin C's effectiveness but also contribute to healthy blood vessels Read Review. Overall, the consensus among users points to a variety of benefits when this supplement is integrated with other dietary support, promoting better vascular health and reducing bruising issues.
Based on user reviews, there seems to be a general consensus on the effectiveness of Vitamin C in treating issues concerning blood vessels, though specific dosage recommendations vary. One user reported that an effective dose for adults is around 500 mg at a time, which they noted as beneficial for veins and blood vessels Read Review. Another user mentioned that a combination of Vitamin C and bioflavonoids is crucial for enhancing blood vessel health, suggesting that such formulations may provide compounded benefits Read Review.
Users also highlighted the supplement's overall quality and digestibility, affirming that they experienced improvements such as reduced bruising and healthier-looking skin after use Read Review, Read Review. The integration of bioflavonoids with Vitamin C was frequently mentioned as a vital factor for maximizing the benefits related to vascular health Read Review. Therefore, while dosage specifics may differ, the focus on Vitamin C combined with bioflavonoids seems prevalent in user experiences aimed at improving vascular strength.
9
Bruising resolved
I struggled with easily bruising, and my blood work indicated large platelets. After starting this supplement, I am pleased to report that I no longer experience bruising issues.
9
Skin tone improvement
Suddenly, I really liked it - it’s no secret that vitamin C is often taken as an adaptogen before the cold season to help strengthen the immune system. This particular supplement contains rutin and hesperidin - vital bioflavonoids for those concerned about their blood vessels. I have second-stage varicose veins and spider veins on my face. With this supplement, I noticed my skin became lighter, the tone was even, and bruises disappeared quickly. I recommend it for strengthening and healthy blood vessels. The capsules are medium-sized, easy to swallow, and the contents can be poured into juice. They have a pleasant herbal scent and do not cause gastrointestinal issues, if that's a concern for anyone.
7.5
Strengthens blood vessels
Vitamin C with bioflavonoids is of excellent quality, with digestible and natural ingredients. The composition is superb, and vitamin C is well absorbed alongside bioflavonoids. The jar and capsules are of average size and well-packaged. My stomach tolerates it well. This unique formula offers comprehensive protection for the immune system of both children and adults, stimulates collagen synthesis, and strengthens the walls of blood vessels, including those prone to varicose veins.
9
Supports veins well
Excellent! This is my favourite form of vitamin C! It’s beneficial for veins and blood vessels! The dosage is 500 mg at a time for adults! If this was useful, please give it a thumbs up!
7.5
Effective vessel support
A very useful formula. Bioflavonoids effectively complement vitamin C, enhancing their ability to strengthen blood vessels and capillaries. The dosage is excellent, providing enough for several courses for the whole family.
4
Vitamin C lowers blood clot risks
Ascorbic acid as an adjunctive therapy in critically ill patients with COVID-19: a propensity score matched study.
We explored the use of ascorbic acid, commonly known as vitamin C, as an additional treatment option for patients critically ill with COVID-19. This study was conducted across two large hospitals in Saudi Arabia and involved a thorough look at the outcomes for these patients, especially concerning blood clotting and overall health.
After evaluating 739 patients, 296 were matched for a fair comparison. Notably, the findings suggest that while there was no significant reduction in mortality rates for those receiving vitamin C compared to those who did not, the use of vitamin C was linked to a lower occurrence of thrombosis—an abnormal blood clotting condition. The incidence of thrombosis in the vitamin C group was 6.1%, compared to 13% in the non-vitamin C group, indicating a possible protective effect against blood clots.
Ultimately, while the addition of vitamin C did not show a direct mortality benefit, it may offer some hope for reducing blood clot complications in these severely affected patients. However, further research will be necessary to validate these findings and clarify the role of vitamin C in treatment protocols for COVID-19.
9
Vitamin C enhances blood clotting
Ascorbic acid improves thrombotic function of platelets during living donor liver transplantation by modulating the function of the E3 ubiquitin ligases c-Cbl and Cbl-b.
We sought to understand how ascorbic acid, commonly known as vitamin C, impacts blood clotting during living donor liver transplantation (LDLT). In our study, we analyzed blood samples from 21 recipients before and after their surgeries.
We employed a well-structured approach, using rotational thromboelastography (TEG) and western blot analysis to scrutinize fibrinolysis and the functionality of specific proteins involved in clotting. Blood samples were tested in three distinct groups, one receiving vitamin C, to see its effects on clot rigidity and fibrinolysis.
Our findings revealed that ascorbic acid notably reduced fibrinolysis, which refers to the breakdown of blood clots, and improved the rigidity of the clots formed. Additionally, we observed that levels of a protein called Cbl-b were higher in those receiving vitamin C, while another protein, c-Cbl, showed reduced phosphorylation. These functional changes might explain how vitamin C supports better clotting during surgeries.
This study indicates that vitamin C could be a beneficial treatment to consider during LDLT to manage hyperfibrinolysis, thus promoting better outcomes for patients undergoing these complex procedures.
2
Vitamin C may promote thrombosis
High-Dose Vitamin C Injection to Cancer Patients May Promote Thrombosis Through Procoagulant Activation of Erythrocytes.
We examined the impact of high doses of vitamin C on blood clotting, particularly focusing on its effect on red blood cells (RBCs). Through our research, we discovered that vitamin C, when injected intravenously in doses of 0.5 to 5 mM, can increase the tendency of RBCs to become procoagulant. This increase was linked to a process where a molecule called phosphatidylserine is exposed on the outer membrane of these cells, which can lead to blood clot formation.
The molecular changes in RBCs were attributed to oxidative stress induced by high vitamin C levels, disrupting important calcium and thiol balance in the cells. Furthermore, our findings showed that administering vitamin C at 0.5 to 1.0 g/kg in rats resulted in a significant increase in thrombosis events. More importantly, RBCs from cancer patients displayed an increased sensitivity to these prothrombotic effects compared to healthy individuals.
Given these observations, it’s crucial to approach high-dose vitamin C therapy with caution, particularly in patients already at a higher risk for blood clotting. While vitamin C is often thought to have health benefits, our study reveals a potential risk that must not be overlooked.
8
Vitamin C reduces clotting factors
Vitamin C suppresses lipopolysaccharide-induced procoagulant response of human monocyte-derived macrophages.
We explored how vitamin C influences blood clotting in response to inflammation, specifically focusing on how it affects certain proteins involved in this process. In our study, we tested vitamin C at clinically relevant doses within human monocyte-derived macrophages. This investigation involved examining its effects on tissue factor (TF) and Factor VII Activating Protease (FSAP), two key proteins that play a role in triggering blood clotting after exposure to lipopolysaccharide (LPS), which is often associated with infection and inflammation.
Our findings showed that vitamin C can prevent the activation of a protein called NF-kB, which is crucial for the inflammatory response. It turns out that vitamin C not only reduces the DNA-binding activity of NF-kB but also decreases the expression of TF and FSAP, suggesting it can effectively modulate clots formed in response to inflammation. Overall, we observed that vitamin C offers promising benefits in altering pro-inflammatory and pro-coagulation processes.
This means that aside from being a potent antioxidant, vitamin C might also support cardiovascular health by reducing the risk factors associated with clot formation during inflammatory responses. While more research is needed to validate these effects fully, our study opens the door to the potential role of vitamin C in managing clot-related disorders linked to inflammation.
References
de Boer HC, Sawhney JS. Pediatric scurvy case report: a novel presentation with deep vein thrombosis secondary to large bilateral spontaneous iliac subperiosteal hematomas. BMC Pediatr. 2024;24:126. doi:10.1186/s12887-024-04579-4
Al Sulaiman K, Aljuhani O, Saleh KB, Badreldin HA, Al Harthi A, et al. Ascorbic acid as an adjunctive therapy in critically ill patients with COVID-19: a propensity score matched study. Sci Rep. 2021;11:17648. doi:10.1038/s41598-021-96703-y
Çelik M, Bayrak A, Duramaz A, Başaran SH, Kızılkaya C, et al. The effect of fibrin clot and C vitamin on the surgical treatment of Achilles tendon injury in the rat model✰. Foot Ankle Surg. 2021;27:681. doi:10.1016/j.fas.2020.09.006
Kwon JH, Kim D, Cho H, Shin BS. Ascorbic acid improves thrombotic function of platelets during living donor liver transplantation by modulating the function of the E3 ubiquitin ligases c-Cbl and Cbl-b. J Int Med Res. 2019;47:1856. doi:10.1177/0300060518817408
Parahuleva MS, Jung J, Burgazli M, Erdogan A, Parviz B, et al. Vitamin C suppresses lipopolysaccharide-induced procoagulant response of human monocyte-derived macrophages. Eur Rev Med Pharmacol Sci. 2016;20:2174.
Kim K, Bae ON, Koh SH, Kang S, Lim KM, et al. High-Dose Vitamin C Injection to Cancer Patients May Promote Thrombosis Through Procoagulant Activation of Erythrocytes. Toxicol Sci. 2015;147:350. doi:10.1093/toxsci/kfv133